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CXCR4 Antikörper (AA 151-300)

CXCR4 Reaktivität: Maus, Ratte WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4908443
  • Target Alle CXCR4 Antikörper anzeigen
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Bindungsspezifität
    • 16
    • 15
    • 15
    • 12
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-300
    Reaktivität
    • 146
    • 85
    • 62
    • 21
    • 10
    • 10
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 117
    • 30
    • 12
    • 9
    • 1
    Kaninchen
    Klonalität
    • 125
    • 44
    Polyklonal
    Konjugat
    • 95
    • 8
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CXCR4 Antikörper ist unkonjugiert
    Applikation
    • 109
    • 58
    • 50
    • 36
    • 26
    • 26
    • 25
    • 25
    • 20
    • 10
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Kreuzreaktivität
    Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse CXCR4
    Isotyp
    IgG
    Top Product
    Discover our top product CXCR4 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Andere Bezeichnung
    CXCR4 (CXCR4 Produkte)
    Hintergrund

    Synonyms: CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, b2b220Clo, PBSF/SDF-1, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Fusin, Leukocyte-derived seven transmembrane domain receptor, Pre-B-cell-derived chemokine receptor, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Cxcr4

    Background: Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity). Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

    Gen-ID
    12767
    UniProt
    P70658
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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