BANP Antikörper

Produktnummer ABIN4906466

Der Maus Monoklonal anti-BANP Antikörper wird verwendet zum Nachweis von BANP in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für BANP Antikörper (ABIN4906466)

Target: BANP (Protein BANP (BANP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BANP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 4C2

Produktdetails anti-BANP Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein G.

Immunogen: This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu BANP

Target: BANP (Protein BANP (BANP))

Andere Bezeichnung: BANP

Hintergrund:

Synonyms: BEND1, SMAR1, SMARBP1, Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BANP

Background: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

Gen-ID: 54971

UniProt: Q8N9N5