PICALM Antikörper

Produktnummer ABIN4904757

Dieses Anti-PICALM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PICALM in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PICALM Antikörper (ABIN4904757)

Target: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PICALM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PICALM Antikörper

Produktmerkmale: This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10,11)(p13,q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PICALM.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu PICALM

Target: PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))

Andere Bezeichnung: PICALM

Gen-ID: 8301

UniProt: Q13492

Pathways: Synaptic Membrane