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Hemoglobin Subunit beta Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Hemoglobin Subunit beta in WB, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN4903870

Kurzübersicht für Hemoglobin Subunit beta Antikörper (ABIN4903870)

Target

Alle Hemoglobin Subunit beta (HBB) Antikörper anzeigen
Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Reaktivität

  • 49
  • 15
  • 12
  • 10
  • 8
  • 3
  • 2
Human, Maus, Ratte

Wirt

  • 62
  • 19
Kaninchen

Klonalität

  • 65
  • 17
Polyklonal

Konjugat

  • 42
  • 13
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Hemoglobin Subunit beta Antikörper ist unkonjugiert

Applikation

  • 69
  • 44
  • 23
  • 21
  • 16
  • 6
  • 5
  • 4
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Produktmerkmale

    Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The å (16p13.3, 5'-Ω-pseudoz-pseudo å2-pseudo å1-å2-å1-1-3') and (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two å chains and two chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between å and chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the å1-2 cleavage plane. When the two å1-2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two å chains plus two chains, comprises 97 % of total circulating hemoglobin. The remaining 3 % of total circulating hemoglobin is comprised of Hb A-2, which consists of two å chains plus two chains, and fetal hemoglobin (Hb F), which consists of two å chains together with two © chains.

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant protein of human HBB.

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:100-1:200 , IHC 1:50-1:100 , FC 1:20-1:50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C.
  • Target

    Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

    Andere Bezeichnung

    HBB

    Gen-ID

    3043

    UniProt

    P68871
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