PPARD Antikörper

Produktnummer ABIN4902153

Dieses Anti-PPARD-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PPARD in IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für PPARD Antikörper (ABIN4902153)

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPARD Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2F9

Produktdetails anti-PPARD Antikörper

Verwendungszweck: PPAR delta is a protein encoded by the PPARD gene which is approximately 49,9 kDa. PPAR delta is localised to the nucleus. It is involved in pyruvate metabolism and the citric acid cycle, gene expression, metabolism and nuclear receptor transcription pathway. This protein falls under the peroxisome proliferator-activated receptor family. It is a nuclear hormone receptor that binds peroxisome proliferators and controls the size and number of peroxisomes produced by cells. It may also function as an integrator of transcription repression and nuclear receptor signalling. PPAR delta is ubiquitously expressed with the highest levels in the placenta and skeletal muscle. Mutations in the PPARD gene may result in atherosclerosis. STJ97707 was developed from clone 2F9 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of PPAR delta.

Spezifität: PPAR Delta Mouse Monoclonal Antibody (2F9) detects endogenous levels of PPAR Delta

Produktmerkmale: Mouse Monoclonal to PPAR Delta.

Aufreinigung: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Recombinant peptide derived from PPAR Delta

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IHC 1:100-200

Kommentare:

Ubiquitous with maximal levels in placenta and skeletal muscle.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu PPARD

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Andere Bezeichnung: PPAR Delta

Gen-ID: 5467

UniProt: Q03181

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation