TFF1 Antikörper

Produktnummer ABIN4901698

Dieser Maus Monoklonal Antikörper detektiert spezifisch TFF1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für TFF1 Antikörper (ABIN4901698)

Target: TFF1 (Trefoil Factor 1 (TFF1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TFF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TFF1 Antikörper

Verwendungszweck: HP-1α is a protein encoded by the CBX5 gene which is approximately 22,2 kDa. HP-1α is localised to the nucleus. It is involved in chromatin regulation and acetylation, E2F mediated regulation of DNA replication and aurora B signalling. It is a highly conserved non-histone protein that falls under the heterochromatin protein family. It has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins. It is also involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. HP-1α is expressed in the liver, nervous system, kidney, eye and intestine. Mutations in the CBX5 gene may result in Reynolds syndrome. STJ98895 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous HP-1α protein.

Spezifität: The antibody detects endogenous HP-1α protein.

Produktmerkmale: Mouse Monoclonal to HP-1α.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant peptide derived from HP-1alpha.

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000
ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu TFF1

Target: TFF1 (Trefoil Factor 1 (TFF1))

Andere Bezeichnung: HP-1alpha

Molekulargewicht: 22kDa

Gen-ID: 23468

UniProt: P45973

Pathways: EGFR Signaling Pathway