Annexin a1 Antikörper (AA 130-180)

Produktnummer ABIN4900980

Dieses Anti-Annexin a1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Annexin a1 in WB, ELISA und IHC (p). Geeignet für Human.

Kurzübersicht für Annexin a1 Antikörper (AA 130-180) (ABIN4900980)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Annexin a1 Antikörper

Bindungsspezifität: AA 130-180

Verwendungszweck: Annexin I is a protein encoded by the ANXA1 gene which is approximately 38,7 kDa. Annexin I is localised to the cell membrane. It is involved in peptide ligand-binding receptors, signalling by GPCR, cytokine signalling in immune system and RET signalling. It is a membrane-localized protein that binds phospholipids and plays an important role in the innate immune response as an effector of glucocorticoid-mediated responses and is a regulator of the inflammatory process. Annexin I is expressed in resting neutrophils. Mutations in the ANXA1 gene may result in hairy cell leukemia. STJ98699 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This primary antibody detects endogenous Annexin I.

Spezifität: The antibody detects endogenous Annexin I.

Produktmerkmale: Rabbit Polyclonal to Annexin I.

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthetic peptide from human Annexin I protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000
IHC-P 1:50-300
ELISA 1:5000-20000

Kommentare:

Detected in resting neutrophils . Detected in peripheral blood T-cells . Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors . Detected in placenta (at protein level) . Detected in liver.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS,  pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: Annexin I

Molekulargewicht: 38kDa

Gen-ID: 301

UniProt: P04083

Pathways: Hormone Transport