CD17 Antikörper

Produktnummer ABIN489936

Dieses Anti--Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von in FACS. Geeignet für Human.

Kurzübersicht für CD17 Antikörper (ABIN489936)

Target: CD17

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: MEM-68

Produktdetails

Verwendungszweck: Anti-Hu CD17 Purified

Spezifität: The mouse monoclonal antibody MEM-68 recognizes CD17, an extracellular membrane lipid moiety lactosylceramide expressed on granulocytes, monocytes and platelets.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Pre-B cell line NALM-6

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 2 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Antigendetails

Target: CD17

Hintergrund: CD17, lactosylceramide, is an ubiquitous glycosphingolipid with uncharged disaccharide headgroup, highly enriched in lipid raft-derived structures. Besides playing a pivotal role in the biosynthesis of complex glycosphingilipids, lactosylceramide is involved in cell-cell and cell-matrix interactions and in signaling events linked to cell differentiation, development, apoptosis and oncogenesis. Lactosylceramide regulates integrin functions and production of nitric oxide. Its expression defines successive stages in the maturation of myeloid cells.,Lactosylceramide