L3MBTL2 Antikörper (AA 1-230)

Produktnummer ABIN4889662

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-L3MBTL2 Antikörper wird verwendet zum Nachweis von L3MBTL2 in Proben von Human. Er wurde validiert für WB und IP.

Kurzübersicht für L3MBTL2 Antikörper (AA 1-230) (ABIN4889662)

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L3MBTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-L3MBTL2 Antikörper

Bindungsspezifität: AA 1-230

Verwendungszweck: L3MBTL2 antibody (pAb)

Aufreinigung: Unpurified

Immunogen: This L3MBTL2 antibody was raised against a His-Tagged fusion protein containing amino acids 1-230 of human L3MBTL2.

Anwendungsinformationen

Applikationshinweise: IP: 10 µL per IP WB: 1:500 - 1:2,000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-L3MBTL2 Antikörper (ABIN4889662)

LaFave, Béguelin, Koche, Teater, Spitzer, Chramiec, Papalexi, Keller, Hricik, Konstantinoff, Micol, Durham, Knutson, Campbell, Blum, Shi, Doud, Krivtsov, Chung, Khodos, de Stanchina, Ouerfelli et al.: "Loss of BAP1 function leads to EZH2-dependent transformation. ..." in: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, (2015) (PubMed).

Details zu L3MBTL2

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Andere Bezeichnung: L3MBTL2

Hintergrund: L3MBTL2 (Lethal (3) malignant brain tumor-like 2 protein) is a putative member of the polycomb group family and is the human homolog of Drosophila Sfmbt, critical for Hox gene silencing. L3MBTL2 contains one FCS-type zinc finger and four MBT (malignant brain tumor) repeats. L3MBTL2 associates with chromatin-remodeling complexes and helps inhibit the expression of proteins that trigger the cells into mitosis. L3MBTL2 is a part of a complex involved in the G0 phase of the cell cycle. This complex contains other proteins such as E2F-6, Max or HP1 gamma, and participates in transcriptional repression.

Molekulargewicht: 90 kDa

Gen-ID: 83746

NCBI Accession: NP_113676