PRNP Antikörper (C-Term)

Produktnummer ABIN4889437

Produktdetails anti-PRNP Antikörper

Target: PRNP (Prion Protein (PRNP))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Rind (Kuh), Schaf

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRNP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: Reacts with full sequence PrP protein of brain tissue from different species (bovin, human, sheep, rat

Kreuzreaktivität: Schaf, Ratte (Rattus)

Kreuzreaktivität (Details): .) Cross reacts with brain tissue from different species (bovin, human, sheep, rat ...)

Aufreinigung: Purified (protein A)

Immunogen: A 15 residue synthetic peptide derived from C-terminal domain of human PrP protein

Klon: 4H7

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:200 - 1:1000) WB(1:200 - 1:1000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Konzentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu PRNP

Target: PRNP (Prion Protein (PRNP))

Andere Bezeichnung: Prion Protein (PrP) (PRNP Produkte)

Synonyme: ASCR antikoerper, AltPrP antikoerper, CD230 antikoerper, CJD antikoerper, GSS antikoerper, KURU antikoerper, PRIP antikoerper, PrP antikoerper, PrP27-30 antikoerper, PrP33-35C antikoerper, PrPc antikoerper, p27-30 antikoerper, Prn antikoerper, Prn-p antikoerper, prp antikoerper, cjd antikoerper, prion antikoerper, prp(c) antikoerper, MGC84114 antikoerper, PRP antikoerper, PRPC antikoerper, Prp antikoerper, SIP antikoerper, PRNP antikoerper, AA960666 antikoerper, AI325101 antikoerper, PrP antikoerper, PrPC antikoerper, PrPSc antikoerper, Prn-i antikoerper, Sinc antikoerper, prP27-30 antikoerper, prP33-35C antikoerper, PrP-1 antikoerper, PrP1 antikoerper, prnprs1 antikoerper, stPrP-1 antikoerper, zgc:123004 antikoerper, prion protein antikoerper, prion protein S homeolog antikoerper, prion protein b antikoerper, PRNP antikoerper, Prnp antikoerper, prnp.S antikoerper, prnpb antikoerper

Hintergrund: PrP is found in high quantity in the brain of humans and animals infected with neurodegenerative diseases known as transmissible spongiform encephalopathies or prion diseases, like: Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI), Gerstmann-Straussler disease (GSD), Huntington disease-like type 1 (HDL1) and kuru in humans, scrapie in sheep and goat, bovine spongiform encephalopathy (BSE) in cattle.

UniProt: P04156

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation