NCDN Antikörper (N-Term)

Produktnummer ABIN4889373

Dieses Anti-NCDN-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NCDN in WB, ELISA und IHC (fro). Geeignet für Human.

Kurzübersicht für NCDN Antikörper (N-Term) (ABIN4889373)

Target: NCDN (Neurochondrin (NCDN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCDN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NCDN Antikörper

Bindungsspezifität: N-Term

Spezifität: Reacts with human 79 kDa NCDN protein

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Cross-reacts with mouse, rat and bovin NCDN proteins.

Aufreinigung: Purified (protein A)

Immunogen: Synthetic peptide derived from N term part of the human NCDN protein.

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu NCDN

Target: NCDN (Neurochondrin (NCDN))

Andere Bezeichnung: Neurochondrin

Hintergrund: Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling By similarity. Required for the spatial learning process. Acts as a negative regulator of Ca2+-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.

UniProt: Q9UBB6