MBD3 Antikörper (C-Term)
Kurzübersicht für MBD3 Antikörper (C-Term) (ABIN4889329)
Target
Alle MBD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Spezifität
- Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology)
-
Aufreinigung
- Purified (protein A)
-
Immunogen
- Synthetic peptide of derived from C terminal part of human MBD3.
-
-
-
-
Applikationshinweise
-
Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Must be reconstituted in distilled water.
-
Konzentration
- 1 mg/mL
-
Buffer
- Tris 0,1M, glycine 0,1M
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
-
Haltbarkeit
- 6 months
-
-
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
-
Andere Bezeichnung
- MBD3
-
Hintergrund
- Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.
-
Gen-ID
- 53615
-
UniProt
- O95983
-
Pathways
- Chromatin Binding
Target
-