FOXO Antikörper (N-Term)

Produktnummer ABIN4889143

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXO in ELISA und WB. Er zeigt eine Reaktivität gegenüber Drosophila melanogaster.

Kurzübersicht für FOXO Antikörper (N-Term) (ABIN4889143)

Target: FOXO (Forkhead Box, Sub-Group O (FOXO))

Reaktivität: Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-FOXO Antikörper

Bindungsspezifität: N-Term

Spezifität: Reacts with the Drosophila melanogaster dFOXO protein

Aufreinigung: Purified (protein A)

Immunogen: Synthetic peptide derived from Nter domain of the Drosophila dFOXO protein.

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:2000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Konzentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu FOXO

Target: FOXO (Forkhead Box, Sub-Group O (FOXO))

Andere Bezeichnung: Forkhead Box Protein O (dFOXO)

Hintergrund: Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.

Gen-ID: 41709

UniProt: Q95V55

Pathways: Cellular Glucan Metabolic Process, Regulation of Cell Size