SNCA Antikörper (Internal Region, pSer87)

Produktnummer ABIN4888969

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SNCA in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für SNCA Antikörper (Internal Region, pSer87) (ABIN4888969)

Target: SNCA (Synuclein, alpha (SNCA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNCA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SNCA Antikörper

Bindungsspezifität: Internal Region, pSer87

Spezifität: Reacts with human Alpha-synuclein pS87

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Cross-reacts with rat, mouse and other species due to sequencehomology.

Aufreinigung: Purified (protein A)

Immunogen: Synthetic peptide derived from internal domain of human Alpha-synuclein containing a phosphoserine at position 87.

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/200 to 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Andere Bezeichnung: alpha-Synuclein

Hintergrund: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity