Streptococcus Oralis Antikörper

Produktnummer ABIN4888517

Produktdetails

Target: Streptococcus Oralis

Reaktivität: Streptococcus

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Confocal Laser Scanning Microscopy (CLSM), ELISA, Flow Cytometry (FACS)

Spezifität: Streptococcus oralis, not crossreact against S.mutans ATCC 25175, P.gingivalis ATCC 33277, F.nucleatum ATCC 25586 [

Produktmerkmale: S. oralis is a gram positive, non-motile, α-haemolytic bacterium that form chains of cocci. Streptococcus oralis is a commensal bacteria and is found in the human oral cavity [1]. S. oralis is a component of the normal human oral microbiota, and is capable of opportunistic pathogenicity. Once regarded as a minor opportunistic pathogen, S. oralis is now considered a significant pathogen that affects immunocompromised individuals and those with hematological malignancy (cancers that affect the blood). In these individuals S. oralis is known to create such complications as bacterial endocarditis, adult respiratory distress syndrome and streptococcal shock [1]. S. oralis is related to S. pneumoniae a common case of otitis media, septicemia, pneumonia, and meningitis in children that results in a significant mortality rate throughout the world [2]. S. oralis is known to be one of the first bacteria to begin to form the plaque biofilm. Research shows that the S. oralis is able to interact with Porphyromonas gingivalis, which is considered to be one of the leading causes of periodontal disease. Periodontal disease is considered the most common disease affecting the human oral cavity [3]. Interesting facts S. oralis has only been reported to cause meningitis in cases where dental work was recently performed [4]. S. oralis is also seeing use as a probiotic to help support a healthy oral cavity. The strain used as the probiotic is modified, and it helps to aid in restoring the mouth with good bacteria and helping to keep out bacteria that degenerate oral health. To do this, S. oralis colonizes sites around teeth such as the gums, and competes with other bacteria

Aufreinigung: Polyclonal immunoglobulins purified by protein A affinity chromatography

Immunogen: S. oralis ATCC 9811 1010 cells inactivated in glutaraldehyde 2.5%v/v

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol. Neutral pH.

Lagerung: 4 °C

Antigendetails

Target: Streptococcus Oralis

Substanzklasse: Bacteria