CD81 Antikörper

Produktnummer ABIN4888503

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD81 in FACS, WB, IP, ICC, Func und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Kaninchen und Cat.

Kurzübersicht für CD81 Antikörper (ABIN4888503)

Target: CD81

Reaktivität: Human, Kaninchen, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: M38

Produktdetails anti-CD81 Antikörper

Verwendungszweck: Anti-Hu CD81 Purified Low Endotoxin

Spezifität: The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Kreuzreaktivität (Details): Human, Feline (Cat), Rabbit

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Endotoxin-Niveau: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogen: MOLT-4 (human T-ALL cell line)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
Flow cytometry: recommended dilution: 1 μg/mL.
Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81

Hintergrund: CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

Gen-ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C