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CD81 Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD81 in FACS, WB, IP, Func, IHC (p) und ICC. Er zeigt eine Reaktivität gegenüber Human, Kaninchen und Cat.
Produktnummer ABIN4888503

Kurzübersicht für CD81 Antikörper (ABIN4888503)

Target

Alle CD81 Antikörper anzeigen
CD81

Reaktivität

  • 208
  • 143
  • 81
  • 25
  • 25
  • 25
  • 17
  • 16
  • 9
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Kaninchen, Cat

Wirt

  • 118
  • 93
  • 41
  • 11
  • 3
  • 3
  • 1
  • 1
Maus

Klonalität

  • 207
  • 56
  • 4
Monoklonal

Konjugat

  • 111
  • 22
  • 19
  • 18
  • 10
  • 7
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD81 Antikörper ist unkonjugiert

Applikation

  • 197
  • 104
  • 85
  • 51
  • 49
  • 41
  • 35
  • 29
  • 29
  • 25
  • 22
  • 14
  • 14
  • 13
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Klon

M38
  • Verwendungszweck

    Anti-Hu CD81 Purified Low Endotoxin

    Spezifität

    The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

    Kreuzreaktivität (Details)

    Human, Feline (Cat), Rabbit

    Aufreinigung

    Purified by protein-A affinity chromatography.

    Reinheit

    > 95 % (by SDS-PAGE)

    Endotoxin-Niveau

    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

    Immunogen

    MOLT-4 (human T-ALL cell line)

    Isotyp

    IgG1
  • Applikationshinweise

    Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
    Flow cytometry: recommended dilution: 1 μg/mL.
    Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Do not freeze.
  • Target

    CD81

    Andere Bezeichnung

    CD81

    Hintergrund

    CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

    Gen-ID

    975

    UniProt

    P60033

    Pathways

    Inositol Metabolic Process, Hepatitis C
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