CD81 Antikörper
Kurzübersicht für CD81 Antikörper (ABIN4888503)
Target
Alle CD81 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD81 Purified Low Endotoxin
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Spezifität
- The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
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Kreuzreaktivität (Details)
- Human, Feline (Cat), Rabbit
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Endotoxin-Niveau
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
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Immunogen
- MOLT-4 (human T-ALL cell line)
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Isotyp
- IgG1
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Applikationshinweise
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Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
Flow cytometry: recommended dilution: 1 μg/mL.
Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- CD81
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Andere Bezeichnung
- CD81
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Hintergrund
- CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28
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Gen-ID
- 975
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UniProt
- P60033
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Pathways
- Inositol Metabolic Process, Hepatitis C
Target
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