CD81 Antikörper

Produktnummer ABIN4888503

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD81 in FACS, WB, IP, Func, IHC (p) und ICC. Er zeigt eine Reaktivität gegenüber Human, Kaninchen und Cat.

Kurzübersicht für CD81 Antikörper (ABIN4888503)

Target: CD81

Reaktivität: Human, Kaninchen, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Klon: M38

Produktdetails anti-CD81 Antikörper

Verwendungszweck: Anti-Hu CD81 Purified Low Endotoxin

Spezifität: The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Kreuzreaktivität (Details): Human, Feline (Cat), Rabbit

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Endotoxin-Niveau: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogen: MOLT-4 (human T-ALL cell line)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
Flow cytometry: recommended dilution: 1 μg/mL.
Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81

Hintergrund: CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

Gen-ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C