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ITGA2 Antikörper

ITGA2 Reaktivität: Human, Non-Human Primate FACS, WB, ELISA, IP, ICC, IHC (fro) Wirt: Maus Monoclonal AK7 unconjugated
Produktnummer ABIN4888501
  • Target Alle ITGA2 Antikörper anzeigen
    ITGA2 (Integrin alpha 2 (ITGA2))
    Reaktivität
    • 122
    • 73
    • 21
    • 11
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Non-Human Primate
    Wirt
    • 78
    • 43
    • 30
    • 7
    • 7
    Maus
    Klonalität
    • 96
    • 72
    Monoklonal
    Konjugat
    • 65
    • 24
    • 19
    • 16
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITGA2 Antikörper ist unkonjugiert
    Applikation
    • 78
    • 65
    • 42
    • 41
    • 16
    • 16
    • 13
    • 11
    • 10
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    The mouse monoclonal antibody AK7 recognizes an extracellular epitope of CD49b, a 160-165 kDa alpha subunit of VLA-2 integrin complex expressed on platelets, megakaryocytes, activated T and B cells, monocytes, epithelial cells, endothelial cells and fibroblasts.
    Kreuzreaktivität (Details)
    Human, Non-Human Primates
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Human platelets
    Klon
    AK7
    Isotyp
    IgG1
    Top Product
    Discover our top product ITGA2 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Immunohistochemistry: Recommended dilution: 5-10 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    ITGA2 (Integrin alpha 2 (ITGA2))
    Andere Bezeichnung
    CD49b / Integrin alpha 2 (ITGA2 Produkte)
    Synonyme
    BR antikoerper, CD49B antikoerper, GPIa antikoerper, HPA-5 antikoerper, VLA-2 antikoerper, VLAA2 antikoerper, DX5 antikoerper, integrin subunit alpha 2 antikoerper, integrin alpha 2 antikoerper, ITGA2 antikoerper, Itga2 antikoerper
    Hintergrund
    Integrin subunit alpha 2,CD49b the integrin alpha 2 chain, associates with CD29 (integrin beta 1 chain) to form VLA-2 integrin complex, which plays a critical role in the processes of lymphocyte adhesion and activation. VLA-2 serves as a receptor for collagen, laminin, and fibronectin and also regulates the extracellular matrix synthesis and organization. CD49b has been used to identify NK cells, and coexpressed with CD223 (LAG-3) it identifies CD4+ T regulatory type 1 cells (Tr1).,ITGA2, VLA-2 alpha, GPIa
    Gen-ID
    3673
    UniProt
    P17301
    Pathways
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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