PVRL1 Antikörper

Produktnummer ABIN4888494

Produktdetails anti-PVRL1 Antikörper

Target: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PVRL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Spezifität: The mouse monoclonal antibody R1.302 recognizes an extracellular epitope on CD111 (also known as Nectin 1), a 75 kDa type I transmembrane glycoprotein broadly expressed on endothelial cells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: NIH/3T3 cells transfected with human CD111

Klon: R1-302

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu PVRL1

Target: PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

Andere Bezeichnung: CD111 (PVRL1 Produkte)

Synonyme: CD111 antikoerper, CLPED1 antikoerper, ED4 antikoerper, HIgR antikoerper, HVEC antikoerper, OFC7 antikoerper, PRR antikoerper, PRR1 antikoerper, PVRR antikoerper, PVRR1 antikoerper, SK-12 antikoerper, nectin-1 antikoerper, prr1 antikoerper, PVRL1 antikoerper, pvrl1 antikoerper, AI835281 antikoerper, AW549174 antikoerper, Cd111 antikoerper, HveC antikoerper, cd111 antikoerper, cd112 antikoerper, clped1 antikoerper, ed4 antikoerper, higr antikoerper, hveb antikoerper, hvec antikoerper, nectin-2 antikoerper, ofc7 antikoerper, prr antikoerper, prr2 antikoerper, pvrl2 antikoerper, pvrl2.L antikoerper, pvrr antikoerper, pvrr1 antikoerper, pvrr2 antikoerper, sk-12 antikoerper, nectin cell adhesion molecule 1 antikoerper, nectin-1 antikoerper, Poliovirus receptor-related protein 1 antikoerper, poliovirus receptor-related 1 (herpesvirus entry mediator C) antikoerper, nectin cell adhesion molecule 2 L homeolog antikoerper, NECTIN1 antikoerper, LOC100145553 antikoerper, pvrl1 antikoerper, nectin1 antikoerper, Nectin1 antikoerper, PVRL1 antikoerper, nectin2.L antikoerper

Hintergrund: Nectin cell adhesion molecule 1,CD111, also known as nectin-1, is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells. It also serves as a target molecule for entry of herpes simplex virus (HSV-1, HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells. CD111 is connected with actin cytoskeleton through afadin. Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.,NECTIN1, ED4, HIgR, HV1S, HVEC, OFC7, PRR1, PVRR, CD111, PVRL1, PVRR1, SK-12, CLPED1

Gen-ID: 5818

UniProt: Q15223

Pathways: Cell-Cell Junction Organization