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ZP1 Antikörper (N-Term)

Dieses Anti-ZP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZP1 in WB. Geeignet für Human und Ratte.
Produktnummer ABIN4886775

Kurzübersicht für ZP1 Antikörper (N-Term) (ABIN4886775)

Target

Alle ZP1 Antikörper anzeigen
ZP1 (Zona Pellucida Glycoprotein 1 (ZP1))

Reaktivität

  • 27
  • 1
  • 1
  • 1
Human, Ratte

Wirt

  • 27
Kaninchen

Klonalität

  • 27
Polyklonal

Konjugat

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ZP1 Antikörper ist unkonjugiert

Applikation

  • 20
  • 13
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 102-139, N-Term

    Verwendungszweck

    Anti-ZP1 Antibody Picoband®

    Sequenz

    HVLEKDGRFH LRVFMEAVLP NGRVDVAQDA TLICPKPD

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-ZP1 Antibody Picoband® (ABIN4886775). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the N-terminus of human ZP1, different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. Gross, M. B. Personal Communication. Baltimore, Md. 6/24/2014. 2. Huang, Hua-Lin, Lv, Chao, Zhao, Ying-Chun, Li, Wen, He, Xue-Mei, Li, Ping, Sha, Ai-Guo, Tian, Xiao, Papasian, Christopher J., Deng, Hong-Wen, Lu, Guang-Xiu, Xiao, Hong-Mei (2014). "Mutant ZP1 in Familial Infertility". New England Journal of Medicine 370 (13): 1220-1226. 3. Rankin, T., Talbot, P., Lee, E., Dean, J. Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss.Development 126: 3847-3855, 1999.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    ZP1 (Zona Pellucida Glycoprotein 1 (ZP1))

    Andere Bezeichnung

    ZP1

    Hintergrund

    Synonyms: Zona pellucida sperm-binding protein 1,Zona pellucida glycoprotein 1,Zp-1,Processed zona pellucida sperm-binding protein 1,ZP1,

    Tissue Specificity: Oocytes.

    Background: Zona pellucida sperm-binding protein 1 (ZP1) is a protein that belopngs to the mammalian zona pellucida. The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. Zp1 ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. And this gene is mapped to chromosome 11q12.2.

    Molekulargewicht

    70 kDa, 100 kDa

    Gen-ID

    22917

    UniProt

    P60852
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