ZP1 Antikörper (N-Term)

Produktnummer ABIN4886775

Produktdetails anti-ZP1 Antikörper

Target: ZP1 (Zona Pellucida Glycoprotein 1 (ZP1))

Bindungsspezifität: AA 102-139, N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Anti-ZP1 Antibody Picoband®

Sequenz: HVLEKDGRFH LRVFMEAVLP NGRVDVAQDA TLICPKPD

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-ZP1 Antibody Picoband® (ABIN4886775). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ZP1, different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Gross, M. B. Personal Communication. Baltimore, Md. 6/24/2014. 2. Huang, Hua-Lin, Lv, Chao, Zhao, Ying-Chun, Li, Wen, He, Xue-Mei, Li, Ping, Sha, Ai-Guo, Tian, Xiao, Papasian, Christopher J., Deng, Hong-Wen, Lu, Guang-Xiu, Xiao, Hong-Mei (2014). "Mutant ZP1 in Familial Infertility". New England Journal of Medicine 370 (13): 1220-1226. 3. Rankin, T., Talbot, P., Lee, E., Dean, J. Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss.Development 126: 3847-3855, 1999.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu ZP1

Target: ZP1 (Zona Pellucida Glycoprotein 1 (ZP1))

Andere Bezeichnung: ZP1 (ZP1 Produkte)

Hintergrund:

Synonyms: Zona pellucida sperm-binding protein 1,Zona pellucida glycoprotein 1,Zp-1,Processed zona pellucida sperm-binding protein 1,ZP1,

Tissue Specificity: Oocytes.

Background: Zona pellucida sperm-binding protein 1 (ZP1) is a protein that belopngs to the mammalian zona pellucida. The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. Zp1 ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. And this gene is mapped to chromosome 11q12.2.

Molekulargewicht: 70 kDa, 100 kDa

Gen-ID: 22917

UniProt: P60852