ZBTB16 Antikörper (AA 1-165)

Produktnummer ABIN4886774

Der Kaninchen Polyklonal Anti-ZBTB16-Antikörper wurde für WB validiert. Er ist geeignet, ZBTB16 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für ZBTB16 Antikörper (AA 1-165) (ABIN4886774)

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZBTB16 Antikörper

Bindungsspezifität: AA 1-165

Verwendungszweck: Anti-Plzf/ZBTB16 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Plzf/ZBTB16 Antibody Picoband® (ABIN4886774). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Plzf recombinant protein (Position: M1-E165).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Kovalovsky D, Uche OU, Eladad S, Hobbs RM, Yi W, Alonzo E, Chua K, Eidson M, et al. (2008). "The BTB-zinc finger transcriptional regulator, PLZF, controls the development of iNKT cell effector functions". Nature Immunology 9 (9): 1055-64. 2. Savage AK, Constantinides MG, Han J, Picard D, Martin E, Li B, Lantz O, Bendelac A (2008). "The transcription factor PLZF (Zbtb16) s the effector program of the NKT cell lineage".Immunity 29 (3): 391-403. 3. Zhang T, Xiong H, Kan LX, Zhang CK, Jiao XF, Fu G, Zhang QH, Lu L, et al. (1999). "Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene".Proceedings of the National Academy of Sciences of the United States of America 96 (20): 11422-7.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu ZBTB16

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Andere Bezeichnung: ZBTB16

Hintergrund:

Synonyms: Zinc finger and BTB domain-containing protein 16,Promyelocytic leukemia zinc finger protein,Zinc finger protein 145,Zinc finger protein PLZF,ZBTB16,PLZF, ZNF145,

Tissue Specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Background: Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene. This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

Molekulargewicht: 74 kDa

Gen-ID: 7704

UniProt: Q05516

Pathways: Positive Regulation of fat Cell Differentiation