Vip Antikörper (Middle Region)

Produktnummer ABIN4886760

Produktdetails anti-Vip Antikörper

Target: Vip (Vasoactive Intestinal Peptide (Vip))

Bindungsspezifität: AA 81-107, Middle Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vip Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: Anti-VIP peptides VIP Antibody

Sequenz: HADGVFTSDF SKLLGQLSAK KYLESLM

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-VIP peptides VIP Antibody (ABIN4886760). Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human VIP, different from the related mouse and rat sequences by four amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunofluorescence, 5 μg/mL, Rat
1. Fahrenkrug J, Emson PC (Sep 1982). "Vasoactive intestinal polypeptide: functional aspects". British Medical Bulletin 38 (3): 265-70. 2. Linder S, Barkhem T, Norberg A, Persson H, Schalling M, Hökfelt T, Magnusson G (Jan 1987). "Structure and expression of the gene encoding the vasoactive intestinal peptide precursor". Proceedings of the National Academy of Sciences of the United States of America 84 (2): 605-9. 3. Said SI (Apr 1986). "Vasoactive intestinal peptide". Journal of Endocrinological Investigation 9 (2): 191-200.

Kommentare:

Antibody can be supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Referenzen für anti-Vip Antikörper (ABIN4886760)

Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

Details zu Vip

Target: Vip (Vasoactive Intestinal Peptide (Vip))

Andere Bezeichnung: VIP (Vip Produkte)

Hintergrund:

Synonyms: VIP peptides,Intestinal peptide PHV-42,Peptide histidine valine 42,Intestinal peptide PHM-27,Peptide histidine methioninamide 27,Vasoactive intestinal peptide,VIP,Vasoactive intestinal polypeptide,VIP,

Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.

Background: Vasoactive intestinal peptide, also known as PHM27 or VIP, is a peptide hormone containing 28 amino acid residues. This gene is mapped to 6q25. The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Molekulargewicht: 26 kDa

Gen-ID: 7432

UniProt: P01282

Pathways: Hormone Activity, cAMP Metabolic Process