PSMA2 Antikörper (Middle Region)

Produktnummer ABIN4886705

Der Kaninchen Polyklonal Anti-PSMA2-Antikörper wurde für WB validiert. Er ist geeignet, PSMA2 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für PSMA2 Antikörper (Middle Region) (ABIN4886705)

Target: PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PSMA2 Antikörper

Bindungsspezifität: AA 82-123, Middle Region

Verwendungszweck: Anti-Proteasome 20S alpha 2/PSMA2 Antibody Picoband®

Sequenz: DYRVLVHRAR KLAQQYYLVY QEPIPTAQLV QRVASVMQEY T

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Proteasome 20S alpha 2/PSMA2 Antibody Picoband® (ABIN4886705). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human PSMA2, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Groll M, Ditzel L, Löwe J, Stock D, Bochtler M, Bartunik HD, Huber R (Apr 1997). "Structure of 20S proteasome from yeast at 2.4 A resolution". Nature 386 (6624): 463-71. 2. Tomko RJ, Hochstrasser M (2013). "Molecular architecture and assembly of the eukaryotic proteasome". Annual Review of Biochemistry 82: 415-45.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu PSMA2

Target: PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Andere Bezeichnung: PSMA2

Hintergrund:

Synonyms: Proteasome subunit alpha type-2,3.4.25.1,Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3,PSMA2,HC3, PSC3,

Tissue Specificity: Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.

Background: Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.

Molekulargewicht: 26 kDa

Gen-ID: 5683

UniProt: P25787

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA