MUC3B Antikörper (C-Term)

Produktnummer ABIN4886675

Der Kaninchen Polyklonal anti-MUC3B Antikörper wird verwendet zum Nachweis von MUC3B in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für MUC3B Antikörper (C-Term) (ABIN4886675)

Target: MUC3B (Mucin 3B, Cell Surface Associated (MUC3B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MUC3B Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-MUC3/MUC3A/MUC3B Antibody

Sequenz: DLNDNTSQAY RDFNKTFWNQ MQKIFADMQG FTFK

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-MUC3/MUC3A/MUC3B Antibody (ABIN4886675). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MUC3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu MUC3B

Target: MUC3B (Mucin 3B, Cell Surface Associated (MUC3B))

Andere Bezeichnung: MUC3B

Hintergrund:

Synonyms: Mucin-3B ,MUC-3B ,Intestinal mucin-3B ,MUC3B ,

Tissue Specificity: Fetal and adult small intestine and fetal and adult colon. .

Background: MUC3 consists of two genes, MUC3A and MUC3B, each encoding membrane-bound mucins possessing 2 epidermal growth factor-like domains. The MUC3 gene is mapped to chromosome 7. It was showed that synthetic peptide-mediated upregulation of MUC3 dramatically inhibited adherence of enteropathogenic E. coli or enterohemorrhage E. coli serotype O157:H7 to HT-29 human intestinal epithelial cells. Peptide stimulation altered expression of a number of transcription factors, including upregulation of SP1, CREB1, and CDX2. These transcription factors bound to consensus sites in the MUC3 promoter upon peptide stimulation and likely mediated MUC3 upregulation.

Molekulargewicht: 345 kDa

Gen-ID: 4584, 57876

UniProt: Q9H195