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HNRNPA1 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-HNRNPA1-Antikörper wurde für WB, IHC, IF, ICC und FACS validiert. Er ist geeignet, HNRNPA1 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN4886621

Kurzübersicht für HNRNPA1 Antikörper (N-Term) (ABIN4886621)

Target

Alle HNRNPA1 Antikörper anzeigen
HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Reaktivität

  • 68
  • 53
  • 46
  • 19
  • 15
  • 9
  • 7
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
Human, Maus, Ratte

Wirt

  • 81
  • 5
Kaninchen

Klonalität

  • 71
  • 15
Polyklonal

Konjugat

  • 42
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HNRNPA1 Antikörper ist unkonjugiert

Applikation

  • 49
  • 28
  • 26
  • 17
  • 13
  • 13
  • 13
  • 10
  • 9
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-42, N-Term

    Verwendungszweck

    Anti-HnRNP A1/HNRNPA1 Antibody Picoband®

    Sequenz

    KEPEQLRKLF IGGLSFETTD ESLRSHFEQW GTLTD

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-HnRNP A1/HNRNPA1 Antibody Picoband® (ABIN4886621). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the N-terminus of human HnRNP A1, identical to the related mouse and rat sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: HNRPA1 heterogeneous nuclear ribonucleoprotein A1". 2. Biamonti G, Buvoli M, Bassi MT, Morandi C, Cobianchi F, Riva S (1989). "Isolation of an active gene encoding human hnRNP protein A1. Evidence for alternative splicing.". J. Mol. Biol. 207 (3): 491-503. 3. Saccone S, Biamonti G, Maugeri S, Bassi MT, Bunone G, Riva S, Della Valle G (Mar 1992). "Assignment of the human heterogeneous nuclear ribonucleoprotein A1 gene (HNRPA1) to chromosome 12q13.1 by cDNA competitive in situ hybridization". Genomics. 12 (1): 171-4.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

    Andere Bezeichnung

    HNRNPA1

    Hintergrund

    Synonyms: Heterogeneous nuclear ribonucleoprotein A1,hnRNP A1,Helix-destabilizing protein,Single-strand RNA-binding protein,hnRNP core protein A1,Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed,HNRNPA1,HNRPA1,

    Tissue Specificity: Expressed in peripheral blood leukocytes.

    Background: Heterogeneous nuclear ribonucleoprotein A1 is a protein that in humans is encoded by the HNRNPA1 gene. This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

    Molekulargewicht

    36 kDa

    Gen-ID

    3178

    UniProt

    P09651
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