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HLTF Antikörper (AA 911-1009)

Dieses Anti-HLTF-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HLTF in WB, ICC und IF. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN4886619

Kurzübersicht für HLTF Antikörper (AA 911-1009) (ABIN4886619)

Target

Alle HLTF Antikörper anzeigen
HLTF (Helicase-Like Transcription Factor (HLTF))

Reaktivität

  • 53
  • 13
  • 13
  • 9
  • 9
  • 7
  • 4
  • 3
  • 3
  • 3
  • 1
Human, Maus, Ratte

Wirt

  • 55
  • 1
Kaninchen

Klonalität

  • 52
  • 4
Polyklonal

Konjugat

  • 31
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HLTF Antikörper ist unkonjugiert

Applikation

  • 30
  • 13
  • 13
  • 12
  • 10
  • 10
  • 10
  • 5
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 911-1009

    Verwendungszweck

    Anti-HLTF Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-HLTF Antibody Picoband® (ABIN4886619). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived human HLTF recombinant protein (Position: S911-L1009). Human HLTF shares 92.9% amino acid (aa) sequence identity with mouse HLTF.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Lin Y, Sheridan PL, Jones KA, Evans GA (Nov 1995). "The HIP116 SNF2/SW12-related transcription factor gene (SNF2L3) is located on human chromosome 3q25.1-q26.1".Genomics 27 (2): 381-2. 2. Unk I, Hajdú I, Blastyák A, Haracska L (Jan 2010). "Role of yeast Rad5 and its human orthologs, HLTF and SHPRH in DNA damage tolerance". DNA Repair (Amst) 9 (3): 257-67.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    HLTF (Helicase-Like Transcription Factor (HLTF))

    Andere Bezeichnung

    HLTF

    Hintergrund

    Synonyms: Helicase-like transcription factor,3.6.4.-,6.3.2.-,DNA-binding protein/plasminogen activator inhibitor 1 regulator,HIP116,RING finger protein 80,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3,Sucrose nonfermenting protein 2-like 3,HLTF,HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1,

    Tissue Specificity: Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. .

    Background: Helicase-like transcription factor is an enzyme that in humans is encoded by the HLTF gene. This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.

    Molekulargewicht

    114 kDa

    Gen-ID

    6596

    UniProt

    Q14527
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