CACYBP Antikörper (N-Term)
Kurzübersicht für CACYBP Antikörper (N-Term) (ABIN4886495)
Target
Alle CACYBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 7-47, N-Term
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                                            Verwendungszweck
- Anti-SIAH Interacting Protein/CACYBP Antibody Picoband®
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                                            Sequenz
- QKDLEEVKVL LEKATRKRVR DALTAEKSKI ETEIKNKMQQ K
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                                            Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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                                            Produktmerkmale
- Anti-SIAH Interacting Protein/CACYBP Antibody (ABIN4886495). Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            Aufreinigung
- Immunogen affinity purified.
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                                            Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human CACYBP, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
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                        Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
 Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
 Immunocytochemistry/Immunofluorescence,2 μg/mL, Human
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 Immunoprecipitation, 0.5-2 μg/mL, Human
 1. Matsuzawa, S., Reed, J. C. Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses.Molec. Cell 7: 915-926, 2001. 2. Sun S, Ning X, Liu J, et al. (2007). "Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma.". Biochem. Biophys. Res. Commun. 356 (4): 864-71.
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                                            Kommentare
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                        Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P). 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Lyophilized
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                                            Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            Konzentration
- 500 μg/mL
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                                            Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Handhabung
- Avoid repeated freezing and thawing.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
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    - CACYBP (Calcyclin Binding Protein (CACYBP))
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                                            Andere Bezeichnung
- CACYBP
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                                            Hintergrund
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                        Synonyms: Calcyclin-binding protein,CacyBP,hCacyBP,S100A6-binding protein,Siah-interacting protein,CACYBP,S100A6BP, SIP,PNAS-107, Tissue Specificity: Widely expressed. Background: Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene. And this gene is mapped to 1q24-q25. The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. In addition, it probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. 
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                                            Molekulargewicht
- 26 kDa
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                                            Gen-ID
- 27101
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                                            Pathways
- Response to Growth Hormone Stimulus
 Target
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