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C1QBP Antikörper (AA 190-282)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch C1QBP in WB, IHC, ICC, IF, FACS und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN4886491

Kurzübersicht für C1QBP Antikörper (AA 190-282) (ABIN4886491)

Target

Alle C1QBP Antikörper anzeigen
C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Reaktivität

  • 93
  • 45
  • 32
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 100
  • 28
  • 1
Kaninchen

Klonalität

  • 89
  • 40
Polyklonal

Konjugat

  • 80
  • 14
  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser C1QBP Antikörper ist unkonjugiert

Applikation

  • 105
  • 54
  • 38
  • 31
  • 24
  • 19
  • 18
  • 13
  • 13
  • 7
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 19
    • 15
    • 12
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 190-282

    Verwendungszweck

    Anti-GC1q R/C1QBP Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-GC1q R/C1QBP Antibody Picoband® (ABIN4886491). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived human GC1q R recombinant protein (Position: E190-Q282). Human GC1q R shares 92.5% and 93.5% amino acid (aa) sequence identity with mouse and rat GC1q R, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: C1QBP complement component 1, q subcomponent binding protein". 2. Deb TB, Datta K (March 1996). "Molecular cloning of human fibroblast hyaluronic acid-binding protein confirms its identity with P-32, a protein co-purified with splicing factor SF2. Hyaluronic acid-binding protein as P-32 protein, co-purified with splicing factor SF2". J Biol Chem 271 (4): 2206-12. 3. Ghebrehiwet B, Lim BL, Peerschke EI, Willis AC, Reid KB (June 1994). "Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q". J Exp Med 179(6): 1809-21.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

    Andere Bezeichnung

    C1QBP

    Hintergrund

    Synonyms: Complement component 1 Q subcomponent-binding protein, mitochondrial,ASF/SF2-associated protein p32,Glycoprotein gC1qBP,C1qBP,Hyaluronan-binding protein 1,Mitochondrial matrix protein p32,gC1q-R protein,p33,C1QBP,GC1QBP, HABP1, SF2P32,

    Tissue Specificity: Expressed on cell surface of peripheral blood cells (at protein level), Surface expression is reported for macrophages and monocyte-derived dendritic cells. .

    Background: Complement component 1 Q subcomponent-binding protein, mitochondrial is a protein that in humans is encoded by the C1QBP gene. This gene is mapped to 17p13.3 in a region conserved with mouse chromosome 11. The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein.

    Molekulargewicht

    35 kDa

    Gen-ID

    708

    UniProt

    Q07021

    Pathways

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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