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Osteocalcin Antikörper (AA 50-95)

BGLAP Reaktivität: Maus IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886486
  • Target Alle Osteocalcin (BGLAP) Antikörper anzeigen
    Osteocalcin (BGLAP)
    Bindungsspezifität
    • 15
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-95
    Reaktivität
    • 101
    • 43
    • 20
    • 20
    • 19
    • 15
    • 15
    • 10
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 91
    • 32
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 95
    • 33
    Polyklonal
    Konjugat
    • 74
    • 13
    • 11
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Osteocalcin Antikörper ist unkonjugiert
    Applikation
    • 97
    • 71
    • 50
    • 15
    • 15
    • 14
    • 14
    • 9
    • 9
    • 8
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Osteocalcin(BGLAP) detection. Tested with IHC-P in Mouse.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Osteocalcin(BGLAP) detection. Tested with IHC-P in Mouse.
    Gene Name: bone gamma-carboxyglutamate (gla) protein
    Protein Name: Osteocalcin
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived mouse Osteocalcin recombinant protein (Position: Y50-I95). Mouse Osteocalcin shares 69% and 68.9% amino acid (aa) sequence identity with human and rat Osteocalcin, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product BGLAP Primärantikörper
  • Applikationshinweise
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Song, Wang, Zeng, Wang: "Synergistic effects of fibroblast growth factor-2 and bone morphogenetic protein-2 on bone induction." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 4483-4492, (2018) (PubMed).

    Yang, Baban, Isales, Shi: "Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss." in: PLoS ONE, Vol. 12, Issue 8, pp. e0181133, (2017) (PubMed).

    Che, Guo, Li, Wang, Wei: "Intramuscular injection of bone marrow mononuclear cells contributes to bone repair following midpalatal expansion in rats." in: Molecular medicine reports, Vol. 13, Issue 1, pp. 681-8, (2016) (PubMed).

    Yin, Cheng, Qin, Yu, Yu, Zhong, Sun, Zhang: "Effects of Naringin on Proliferation and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells In Vitro and In Vivo." in: Stem cells international, Vol. 2015, pp. 758706, (2015) (PubMed).

    Cheng, Wang, Zhang, Shi: "The osteogenic potential of mesoporous bioglasses/silk and non-mesoporous bioglasses/silk scaffolds in ovariectomized rats: in vitro and in vivo evaluation." in: PLoS ONE, Vol. 8, Issue 11, pp. e81014, (2014) (PubMed).

    Chen, Bai, Liao, Peng, Wu, Wang, Zeng, Xie: "Electrospun poly(L-lactide)/poly(?-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71265, (2013) (PubMed).

  • Target
    Osteocalcin (BGLAP)
    Andere Bezeichnung
    BGLAP (BGLAP Produkte)
    Synonyme
    BGP antikoerper, OC antikoerper, OCN antikoerper, Bglap1 antikoerper, Bglap2 antikoerper, OG1 antikoerper, mOC-A antikoerper, Bgp antikoerper, Bgpr antikoerper, Bgpra antikoerper, bgp antikoerper, LOC792433 antikoerper, ocn antikoerper, GLA antikoerper, BGLAP antikoerper, PMF1 antikoerper, bone gamma-carboxyglutamate protein antikoerper, bone gamma carboxyglutamate protein antikoerper, bone gamma-carboxyglutamate protein S homeolog antikoerper, bone gamma-carboxyglutamate (gla) protein antikoerper, osteocalcin antikoerper, polyamine-modulated factor 1 antikoerper, BGLAP antikoerper, Bglap antikoerper, bglap.S antikoerper, bglap antikoerper, ocn antikoerper, LOC100529177 antikoerper, LOC100146589 antikoerper
    Hintergrund
    Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time directing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.

    Synonyms: BGLAP | Bone Gla protein | ocn | OSTCN HUMAN | Osteocalcin | P86546
    Gen-ID
    12096
    UniProt
    P86546
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