BDKRB2 Antikörper (C-Term)

Produktnummer ABIN4886484

Dieses Anti-BDKRB2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BDKRB2 in WB. Geeignet für Human.

Kurzübersicht für BDKRB2 Antikörper (C-Term) (ABIN4886484)

Target: BDKRB2 (Bradykinin Receptor B2 (BDKRB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BDKRB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BDKRB2 Antikörper

Bindungsspezifität: AA 357-391, C-Term

Verwendungszweck: Anti-BDKRB2 Antibody Picoband®

Sequenz: RSEPIQMENS MGTLRTSISV ERQIHKLQDW AGSRQ

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-BDKRB2 Antibody Picoband® (ABIN4886484). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human BDKRB2, different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human
1. Fernandes L, Fortes ZB, Nigro D, Tostes RC, Santos RA, Catelli De Carvalho MH (2001). "Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneously hypertensive rats studied in vivo".Hypertension 37 (2 Part 2): 703-9. 2. Hess JF, Borkowski JA, Young GS, et al. (1992). "Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor.". Biochem. Biophys. Res. Commun. 184 (1): 260-8.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu BDKRB2

Target: BDKRB2 (Bradykinin Receptor B2 (BDKRB2))

Andere Bezeichnung: BDKRB2

Hintergrund:

Synonyms: B2 bradykinin receptor,B2R,BK-2 receptor,BDKRB2,BKR2,

Tissue Specificity: Ubiquitous. Widespread in normal smooth muscle tissue and neurons. .

Background: Bradykinin receptor B2 is a G-protein coupled receptor forbradykinin, encoded by the BDKRB2 gene in humans. This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.

Molekulargewicht: 50 kDa

Gen-ID: 624

UniProt: P30411

Pathways: ACE Inhibitor Pathway, Negative Regulation of intrinsic apoptotic Signaling