AFG3L2 Antikörper (AA 168-250)

Produktnummer ABIN4886437

Produktdetails anti-AFG3L2 Antikörper

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Bindungsspezifität: AA 168-250

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFG3L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for AFG3-like protein 2(AFG3L2) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for AFG3-like protein 2(AFG3L2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: AFG3 like matrix AAA peptidase subunit 2
Protein Name: AFG3-like protein 2

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human AFG3L2 recombinant protein (Position: R168-D250). Human AFG3L2 shares 100% amino acid (aa) sequence identity with mouse AFG3L2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Andere Bezeichnung: AFG3L2 (AFG3L2 Produkte)

Hintergrund: AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. In humans, it is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.

Synonyms: AFG3 like protein 2 | AFG3-like protein 2 | AFG3L2 | SCA28 | Spinocerebellar ataxia 28 | Q9Y4W6

Gen-ID: 10939

UniProt: Q9Y4W6

Pathways: Skeletal Muscle Fiber Development