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ADA Antikörper (AA 135-363)

ADA Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886424
  • Target Alle ADA Antikörper anzeigen
    ADA (Adenosine Deaminase (ADA))
    Bindungsspezifität
    • 15
    • 15
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 135-363
    Reaktivität
    • 65
    • 33
    • 18
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 74
    • 22
    • 1
    Kaninchen
    Klonalität
    • 77
    • 20
    Polyklonal
    Konjugat
    • 47
    • 11
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADA Antikörper ist unkonjugiert
    Applikation
    • 84
    • 46
    • 13
    • 13
    • 13
    • 12
    • 11
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Adenosine deaminase(ADA) detection. Tested with WB, IHC-P in Human.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Adenosine deaminase(ADA) detection. Tested with WB, IHC-P in Human.
    Gene Name: adenosine deaminase
    Protein Name: Adenosine deaminase
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived human ADA recombinant protein (Position: Q135-L363). Human ADA shares 82.5% and 82.9% amino acid (aa) sequence identity with mouse and rat ADA, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product ADA Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    ADA (Adenosine Deaminase (ADA))
    Andere Bezeichnung
    ADA (ADA Produkte)
    Synonyme
    ADA-like antikoerper, xada antikoerper, ADA antikoerper, CG11994 antikoerper, Dmel\\CG11994 antikoerper, DrosADA antikoerper, dADA antikoerper, zgc:92028 antikoerper, adenosine deaminase antikoerper, adenosine deaminase S homeolog antikoerper, Adenosine deaminase antikoerper, ADA antikoerper, Ada antikoerper, ada.S antikoerper, ada antikoerper
    Hintergrund
    Adenosine Deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism. Primarily, ADA in humans is involved in the development and maintenance of the immune system. However, ADA association has also been observed with epithelial cell differentiation, neurotransmission, and gestation maintenance. It has also been proposed that ADA, in addition to adenosine breakdown, stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins. Adenosine deaminase deficiency leads to pulmonary fibrosis, suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them. It has also been recognized that adenosine deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1 alpha, which in part explains the attenuated levels of adenosine in HIF-1 alpha expressing hearts during ischemic stress.

    Synonyms: ADA | ADA1 | ADA 1 | Adenosine aminohydrolase | Adenosine deaminase | P00813
    Gen-ID
    100
    UniProt
    P00813
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process
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