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BAIAP2L1 Antikörper (AA 1-226)

Der Rabbit Polyclonal Anti-BAIAP2L1-Antikörper wurde für WB, IF, IHC (fro) validiert. Er ist geeignet, BAIAP2L1 in Proben von Human, Mouse, Rat zu detektieren.
Produktnummer ABIN488102

Kurzübersicht für BAIAP2L1 Antikörper (AA 1-226) (ABIN488102)

Target

Alle BAIAP2L1 Antikörper anzeigen
BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Reaktivität

Human, Maus, Ratte

Wirt

  • 26
  • 3
Kaninchen

Klonalität

  • 26
  • 3
Polyklonal

Konjugat

  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BAIAP2L1 Antikörper ist unkonjugiert

Applikation

  • 17
  • 13
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-226

    Spezifität

    Recognizes BAIAP2L1.

    Kreuzreaktivität (Details)

    Species reactivity (expected):Mouse (94 %) and Rat (94 %).
    Species reactivity (tested):Human.

    Aufreinigung

    Antigen-Affinity Chromatography

    Immunogen

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 226 of BAIAP2L1 Genename: BAIAP2L1
  • Applikationshinweise

    Western blot: 1/500-1/3000. Positive Controls: 293T, A431, HeLa, HepG2. Immunofluorescence: 1/100-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.55 mg/mL

    Buffer

    0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7), 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store the antibody undiluted (in aliquots) at -20 °C.
  • Target

    BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

    Andere Bezeichnung

    BAIAP2L1

    Hintergrund

    This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq].Synonyms: BAI1-associated protein 2-like 1, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, IRTKS, Insulin receptor tyrosine kinase substrate

    Gen-ID

    55971, 9606

    UniProt

    Q9UHR4

    Pathways

    Regulation of Actin Filament Polymerization
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