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MORF4L1 Antikörper (N-Term)

Der Ziege Polyklonal Anti-MORF4L1-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, MORF4L1 in Proben von Human, Maus, Ratte, Rind (Kuh) und Hund zu detektieren.
Produktnummer ABIN487997

Kurzübersicht für MORF4L1 Antikörper (N-Term) (ABIN487997)

Target

Alle MORF4L1 Antikörper anzeigen
MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

Reaktivität

  • 44
  • 44
  • 23
  • 9
  • 9
  • 8
  • 8
  • 8
  • 7
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Hund

Wirt

  • 55
  • 3
  • 2
Ziege

Klonalität

  • 57
  • 3
Polyklonal

Konjugat

  • 31
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MORF4L1 Antikörper ist unkonjugiert

Applikation

  • 44
  • 16
  • 14
  • 14
  • 12
  • 7
  • 7
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    APKQDPKPKF QEG-C

    Spezifität

    This antibody recognizes MRG15 and is expected to recognise Isoform 1 (NP_006782.1) and Isoform 2 (NP_996670.1).

    Kreuzreaktivität (Details)

    Species reactivity (expected):Mouse, Rat, Porcine, Bovine.
    Species reactivity (tested):Human.

    Aufreinigung

    Affinity Chromatography

    Immunogen

    Syntehtic peptide from the N-Terminus of Human MORF4L1 (NP_006782.1, NP_996670.1) . Genename: MORF4L1
  • Applikationshinweise

    Peptide ELISA: 1/64000. Western blot: Preliminary experiments gave an approx 40 kDa band in Human Liver lysatesand an approx 100 kDa band in Human Heart lysates at 1 μg/mL. Please note that currentlywe cannot find an explanation in the literature for the bands we observe given thecalculated size of 37.0 kDda according to NP_006782.1. Immunohistochemistry on paraffin sections: Human Uterus shows nuclear staining in theepithelial cells of the endometrial glands. Recommended concentration: 2 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

    Andere Bezeichnung

    MRG15

    Hintergrund

    MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.Synonyms: FWP006, HSPC008, HSPC061, MORF-related gene 15 protein, MORF4L1, MRG15, MSL3-1 protein, Mortality factor 4-like protein 1, PP368, Transcription factor-like protein MRG15

    Molekulargewicht

    37.2 kDa (Mouse NP_077751.1).

    Gen-ID

    10933

    NCBI Accession

    NP_006782

    UniProt

    Q9UBU8

    Pathways

    Chromatin Binding
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