ELISA: 0.625 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
6.38 mg/mL (U.V.abs at 280nm)
Buffer
20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody (in aliquots) at-20 °C.
Target
Imipramine
Substanzklasse
Chemical
Hintergrund
Tricyclic antidepressants contain a characteristic three ringed nucleus structure. They act primarily as serotoninnorepinephrine reuptake inhibitors. Tricyclic antidepressants are mainly used as antidepressants, but have also been for the treatment of anxiety disorders and attention hyperactivity disorder and as an adjunct to certain analgesics to treat chronic pain. In many treatments they have been replaced by other compounds with fewer sideeffects. Tricyclic antidepressants are not considered addictive and have a low abuse potential, but suddenly discontinuing treatment may results in discontinuation syndrome and overdose is a main cause of death from prescription drugs. They have significant cardiovascular and neurological toxicity. Monitoring of TCA levels can help determine toxicity, monitor compliance and establish individual target concentrations. Imipramine is a member of the family of tricyclic antidepressants. Its clinical effect is hypothesized as being due to potentiation of adrenergic synapses by blocking uptake of norepinephrine at nerve endings. Imipramine is a very powerful antidepressant and is converted to desipramine in the body.Synonyms: Antideprin, Berkomine, Cristalia, Melipramine, Prazepine, Sermonil, Tricyclic Antidepressant