Macrophage/Monocyte Antikörper

Produktnummer ABIN481685

Der Ratte Monoklonal anti-Macrophage/Monocyte Antikörper wird verwendet zum Nachweis von Macrophage/Monocyte in Proben von Maus. Er wurde validiert für IHC und IHC (p).

Kurzübersicht für Macrophage/Monocyte Antikörper (ABIN481685)

Target: Macrophage/Monocyte

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ER-HR3

Produktdetails

Spezifität: The antigen is found on mouse monocytes and a subset of macrophages. The epitope has not been further characterized. Antigen distribution: Isolated cells: The antigen is found on up to 70 % of circulating monocytes, all other leukocytes are ER-HR 3 negative. It is also found on a subpopulation (about 30 %) of bone marrow cells, mainly consisting of myeloid cells. Tissue sections: In the adult mouse, the antigen is found on distinct subpopulations of resident tissue macrophages in various organs. It is found on a subpopulation of the splenic red pulp macrophages, in the mesenteric lymphoid paracortex, interfollicular areas of Peyer's patches and bone marrow. Epidermal Langerhans cells also express the antigen, whereas macrophages in the connective tissue of the dermis and the gastrointestinal tract only scarcely express the ER-HR 3 related antigen. In the kidney, ER-HR 3 positive macrophages belong to the type 2 interstitial cells in the outer medulla which are negative with BM 8. Distinct ER-HR 3 positive macrophage subpopulations are found in various embryological organs where haematopoietic islands occur, and where they are closely associated with erythrocyte precursor cells. Specificity: Mouse: subpopulation of mature macrophages. Other species: not tested

Aufreinigung: Affinity purified

Immunogen: Adherent bone marrow cells

Isotyp: IgG2c

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (1:100)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Antigendetails

Target: Macrophage/Monocyte

Andere Bezeichnung: Monocytes, Macrophages