Macrophages Antikörper

Produktnummer ABIN481657

Dieser Maus Monoklonal Antikörper detektiert spezifisch Macrophages in IHC (fro) und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Macrophages Antikörper (ABIN481657)

Target: Macrophages

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)

Klon: PM-2K

Produktdetails

Spezifität: The antigen of 150  kDa m.w. is found in the macrophage cell membrane. The epitope has not been determined. Antigen distribution: Isolated cells: Positive on >90 % of alveolar macrophages, and on 10 % of adherent peritoneal cells after 1 day culture. Negative on dendritic cells, on freshly isolated blood monocytes or peritoneal cells, and on bone marrow cells including monocytes, myelomonocytic precursors and megakaryocytes. Tissue sections: PM-2K stains most tissue macrophages in lymphoreticular organs such as thymus, spleen, lymph node and tonsil. It is positive on Kupffer cells of the liver, alveolar macrophages and macrophages in the interstitial tissues of the kidney, pancreas and many other organs. In Gaucher's disease multicentric reticulohistiocytosis and malignant histiocytosis proliferating macrophages are positive. In MFH infiltrating macrophages are stained but not tumour cells. Some bone stromal cells but not osteoclast-like multinucleated giant cells are stained in GCT. Microglial cells, osteoclasts and dendritic cells such as Langerhans cells, interdigitating cells and follicular dendritic cells are negative. Specificity: Human: Macrophages. Other: positive on macrophages of cat, dog, pig, bovine and monkey, negative in rabbit, rat, guinea pig, gold hamster, goat, horse.

Aufreinigung: Affinity purified

Immunogen: Cultured human peritoneal macrophages

Type of Immunogen: Cells

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-Fr (1:400)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Antigendetails

Target: Macrophages