Defensin Antikörper

Produktnummer ABIN481654

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Defensin in IHC und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Defensin Antikörper (ABIN481654)

Target: Defensin (DEF)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: Def-3

Produktdetails anti-Defensin Antikörper

Spezifität: Several defensins are recognized, the epitope has not been further characterized. Biological functions: Various functions have been described for defensins. They are antibacterial, antifungal, chemotactic for monocytes, inhibitory for ACTH-induced corticosteroid synthesis and cytotoxic for cells. Defensins are inhibited by glucosaminoglycans (self protection for cells) and high concentrations of Calpha 2+ ions. Biochemistry: Defensins are a group of cyclic peptides containing 29-35 amino acids (MW < 3500) which tend to form aggregates. The molecules are protease resistant. The defensin content of azurophilic granules in neutrophils is approximately 30 % of the total protein. Specificity: Human: Defensin 1-3 (HNP-1 to HNP-3) in human neutrophils. Synthetic defensin-1 and -2 (Bachem, Bubendorf CH) stain also positively. Not tested with Defensin-4. A side reaction to elastin has been observed in humans. Other: not tested. Defensins have been described in rabbits (NP-1 to NP-5, NP3a = Corticostatin), and in mice (cryptodin).

Aufreinigung: Affinity purified

Immunogen: Native defensins

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (1:1000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 5 mg/mL BSA, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu Defensin

Target: Defensin (DEF)

Andere Bezeichnung: DEF / Defensin

Pathways: Production of Molecular Mediator of Immune Response