Insulin C-Peptide Antikörper
Kurzübersicht für Insulin C-Peptide Antikörper (ABIN472131)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes rat C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Recognizes rat and mouse C-peptide I and rat C-peptide II with equal affinity. Reacts weakly with mouse C-peptide II. It does not recognize rat proinsulin. May be used as a capture antibody in ELISA assays for rat or mouse C-peptides I or II.
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Aufreinigung
- Affinity purified
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Immunogen
- Fragments of rat C-peptide conjugated to a carrier protein.
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Isotyp
- IgG1
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Applikationshinweise
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Approved: ELISA, SwELISA
Usage: ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA ?to detect rat C-peptide I together with LS-C58408 as a detection reagent. These sandwich ELISA combinations are not suitable for the detection of mouse C-peptide I or II. -
Kommentare
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Target Species of Antibody: Rat
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
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Short term: -20°C
Long term: -20°C.
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- Insulin C-Peptide
Target
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