Desmoglein 1/2 Antikörper (C-Term)
DSG1/2
Reaktivität: Rind (Kuh), Human, Maus, Ratte
IHC, IHC (fro), IHC (p), WB, IF
Wirt: Maus
Monoclonal
unconjugated
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- Target Alle Desmoglein 1/2 (DSG1/2) Produkte
- Desmoglein 1/2 (DSG1/2)
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Bindungsspezifität
- C-Term
- Reaktivität
- Rind (Kuh), Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Desmoglein 1/2 Antikörper ist unkonjugiert
- Applikation
- Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunofluorescence (IF)
- Spezifität
- Species (tested so far) Human, bovine, rat, mouse. Recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells, does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting: Mr 165000 Desmoglein, 'band 3' polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ('RUD') of the cytoplasmic C-terminal part of the polypeptide. Reactivities on Cultured Cell Lines (tested so far): A-431, MCF-7, TR-146, PLC and various other human epithelial cell lines, bovine BMGE+H, BMGE-H, MDBK.
- Aufreinigung
- Protein A purified
- Immunogen
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Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis.
Type of Immunogen: Protein - Isotyp
- IgG1
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- Applikationshinweise
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Approved: IF, IHC, IHC-Fr, IHC-P, WB
Usage: Suitable for use in Immunohistochemistry (frozen sections, paraffin-embedded tissue after microwave treatment), Western Blot, Cryo, Paraffin (Microwave), Immunofluorescence microscopy. Immunohistochemistry: 1:10 with PBS, pH 7.4, Incubation Time 1 h at RT, extended with paraffin. - Kommentare
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Target Species of Antibody: Bovine
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- deionized water
- Konzentration
- Lot specific
- Buffer
- Lyophilized.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- Target
- Desmoglein 1/2 (DSG1/2)
- Andere Bezeichnung
- Desmoglein 1/2 (DSG1/DSG2) (DSG1/2 Produkte)
- Synonyme
- DSG1 antikoerper, desmoglein 1 antikoerper, DSG1 antikoerper
- Hintergrund
- This antibody detects: DSG1+2 / Desmoglein 1+2
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