Cardiac Troponin T2 Antikörper (Exon 10)

Produktnummer ABIN462337

Dieser Maus Monoklonal Antikörper erkennt spezifisch Cardiac Troponin T2 in IHC, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Huhn, Pferd, Schaf und Affe.

Kurzübersicht für Cardiac Troponin T2 Antikörper (Exon 10) (ABIN462337)

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Huhn, Pferd, Schaf, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cardiac Troponin T2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Cardiac Troponin T2 Antikörper

Bindungsspezifität: Exon 10

Spezifität: Recognizes the cardiac isoform of rabbit Troponin T (cTnT). Species cross-reactivity: Canine, chicken, goldfish, guinea pig, human, mouse, porcine, rat, sparrow. Does not react with frog.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Chicken, Platypus, Lizard (100%) Hamster, Opossum (90%).

Aufreinigung: Protein G purified

Immunogen: Purified rabbit cardiac troponin T isoform (TnT4R). Epitope: FMPNLVPPKI (5' region of the cardiac gene exon 10). Cellular Localization: Mostly over the I bands in myofibrils. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Chicken, Platypus, Lizard (100%), Hamster, Opossum (90%).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: IF, IHC, IHC-P (1:50)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL. The antibody is also suitable for electron microscopy and immunofluorescence.

Kommentare:

Target Species of Antibody: Rabbit

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.2 % BSA, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu Cardiac Troponin T2

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Andere Bezeichnung: TNNT2 / CTNT

Hintergrund: Name/Gene ID: TNNT2

Synonyms: TNNT2, Cardiomyopathy, hypertrophic 2, CMPD2, CMD1D, CMH2, Cardiac muscle troponin T, Cardiac Troponin T, LVNC6, TnTC, Troponin T type 2 (cardiac), Troponin T, cardiac muscle, Troponin T2, cardiac, CTnT, RCM3

Gen-ID: 7139

UniProt: P45379