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PTCHD2 Antikörper (Middle Region)

PTCHD2 Reaktivität: Human, Maus, Ratte IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4620591
$705.60
Zzgl. Versandkosten $45.00
0.1 mg
Available
  • Target Alle PTCHD2 Antikörper anzeigen
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Bindungsspezifität
    • 15
    • 11
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 47
    • 10
    • 9
    • 4
    • 4
    • 4
    • 4
    Human, Maus, Ratte
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PTCHD2 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 22
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse, Rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    19 amino acid synthetic peptide from near the center of human PTCHD2
    Isotyp
    IgG
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Andere Bezeichnung
    PTCHD2 (PTCHD2 Produkte)
    Synonyme
    DISP3 antikoerper, G630052C06Rik antikoerper, RNDEu-2 antikoerper, RGD1305820 antikoerper, dispatched RND transporter family member 3 antikoerper, patched domain-containing protein 2 antikoerper, si:dkey-32e23.6 antikoerper, DISP3 antikoerper, LOC100082708 antikoerper, si:dkey-32e23.6 antikoerper, disp3 antikoerper, Disp3 antikoerper
    Hintergrund
    PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.Synonyms: DISP3, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3
    Gen-ID
    57540
    UniProt
    Q9P2K9
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