PTCHD2 Antikörper (Middle Region)

Produktnummer ABIN4620591

Dieses Anti-PTCHD2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PTCHD2 in WB und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für PTCHD2 Antikörper (Middle Region) (ABIN4620591)

Target: PTCHD2 (Patched Domain Containing 2 (PTCHD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTCHD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PTCHD2 Antikörper

Bindungsspezifität: Middle Region

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide from near the center of human PTCHD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PTCHD2

Target: PTCHD2 (Patched Domain Containing 2 (PTCHD2))

Andere Bezeichnung: PTCHD2

Hintergrund: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.Synonyms: DISP3, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3

Gen-ID: 57540

UniProt: Q9P2K9