Sphingomyelin Synthase 2 Antikörper

Produktnummer ABIN4620351

Der Kaninchen Polyklonal anti-Sphingomyelin Synthase 2 Antikörper (ABIN4620351) detektiert spezifisch Sphingomyelin Synthase 2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Sphingomyelin Synthase 2 Antikörper (ABIN4620351)

Target: Sphingomyelin Synthase 2 (SGMS2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sphingomyelin Synthase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Sphingomyelin Synthase 2 Antikörper

Spezifität: This antibody detects Sphingomyelin Synthase 2.

Aufreinigung: Antigen Immunoaffinity Chromatography

Immunogen: Synthetic peptide derived from the Human Sphingomyelin Synthase 2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/400 as starting dilution. Immunohistochemistry: 1/400 as starting dilution. Positive control: Brain, heart, kidney, liver, muscle and stomach.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Sphingomyelin Synthase 2

Target: Sphingomyelin Synthase 2 (SGMS2)

Andere Bezeichnung: SGMS2

Hintergrund: Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.Synonyms: SMS2, Sphingomyelin synthase 2

Gen-ID: 166929

NCBI Accession: NP_001129729

UniProt: Q8NHU3