SGPP2 Antikörper

Produktnummer ABIN4620340

Produktdetails anti-SGPP2 Antikörper

Target: SGPP2 (Sphingosine-1-Phosphate Phosphatase 2 (SGPP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGPP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to Sphingosine 1-Phosphate Phosphatase 2.

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 2 protein.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 400, Tissue lysate should be used at 10 - 50 g/lane.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Ship on dry ice. Store (in aliquots) at -20 °C only.

Details zu SGPP2

Target: SGPP2 (Sphingosine-1-Phosphate Phosphatase 2 (SGPP2))

Andere Bezeichnung: SGPP2 (SGPP2 Produkte)

Hintergrund: Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1 - 5)/Gprotein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. SPPase2 is localized to the endoplasmic reticulum. The enzymatic activity and localization of SPPase2 are similar to SPPase1. The tissue expression of SPPase2 was different from that of SPPase1. SPPase2 is an important member of the SPPase family which play a role in attenuating intracellular S1P signaling.Synonyms: SPPase2, Sphingosine-1-phosphatase 2, Sphingosine-1-phosphate phosphatase 2

Gen-ID: 130367

NCBI Accession: NP_689599

UniProt: Q8IWX5