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Fibrinogen Antikörper

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch Fibrinogen in IEP, ID und RID. Er zeigt eine Reaktivität gegenüber Kaninchen.
Produktnummer ABIN458587

Kurzübersicht für Fibrinogen Antikörper (ABIN458587)

Target

Alle Fibrinogen Antikörper anzeigen
Fibrinogen

Reaktivität

  • 99
  • 39
  • 33
  • 27
  • 13
  • 7
  • 5
  • 1
  • 1
Kaninchen

Wirt

  • 86
  • 57
  • 39
  • 13
  • 2
  • 2
Ziege

Klonalität

  • 157
  • 41
Polyklonal

Konjugat

  • 80
  • 26
  • 24
  • 18
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
Dieser Fibrinogen Antikörper ist unkonjugiert

Applikation

  • 79
  • 77
  • 51
  • 51
  • 34
  • 29
  • 28
  • 28
  • 26
  • 22
  • 20
  • 19
  • 13
  • 12
  • 9
  • 8
  • 7
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunoelectrophoresis (IEP), Immunodiffusion (ID), Radial Immunodiffusion (RID)
  • Spezifität

    The antiserum does not cross react with any other component of rabbit plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. of this antiserum has not been tested in detail.

    Produktmerkmale

    Precipitating polyclonal goat antiserum to rabbit fibrinogen

    Aufreinigung

    Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies cross reacting with other with other serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.

    Immunogen

    Fibrinogen (clotting factor I) is a heat labile beta glycoprotein present in plasma. It is the precursor of fibrin, which is the key protein constituting the network of the blood clot. Thrombin converts fibrinogen to fibrin by limited proteolysis. Fibrin monomers polymerize to fibrin which is stabilized by cross-linking. Fibrinogen is isolated from fresh plasma after removing prothrombin. Freund’s complete adjuvant is used in the first step of the immunization procedure.

    Isotyp

    IgG
  • Applikationshinweise

    In precipitating techniques as immunoelectrophoresis and single or double radial immunodiffusion to identify the presence of fibrinogen in rabbit plasma or other body fluids or to determine its concentration.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Konzentration

    Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal goat serum. No foreign proteins added. Antibody titre: Precipitin titre 1:32 when tested against pooled normal rabbit plasma in agar-block immunodiffusion titra

    Buffer

    Delipidated, heat inactivated, lyophilized, stable whole antiserum

    Konservierungsmittel

    Without preservative

    Lagerung

    4 °C

    Informationen zur Lagerung

    The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C
  • Target

    Fibrinogen

    Hintergrund

    The reactivity of the antiserum is restricted to rabbit fibrinogen molecule. In immunoelectrophoresis and radial immunodiffusion, using various antiserum concentrations against normal rabbit plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified fibrinogen. No reaction is obtained with any other plasma protein components or serum. However, the antiserum may also react with fibrin monomers, circulating fibrinopeptides and fibrin degradation products
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