TTR Antikörper

Produktnummer ABIN458186

Produktdetails anti-TTR Antikörper

Target: TTR (Transthyretin (TTR))

Reaktivität: Human

Wirt: Schwein

Klonalität: Polyklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Immunoelectrophoresis (IEP)

Spezifität: Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. of this antiserum has not been tested in detail.

Produktmerkmale: Precipitating polyclonal swine antiserum to human transthyretin (prealbumin)

Aufreinigung: Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other human serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.

Immunogen: Transthyretin is the fastest protein in the immunoelectrophoresis pattern of human serum. It consists of four identical polypeptide chins with no carbohydrate. The molecular weight is 55,000 and the concentration in normal serum ranges from 100 to 400 µ g/ml. It can bind thyroxine and retinal and its concentration is reduced in severe liver diseases. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: In precipitating techniques as immunoelectrophoresis and single and double radial immuno-diffusion (Mancini, Ouchterlony) to identify the presence of transthyretin or to determine its concentration. The presence of non-precipitating antibodies has not been assayed. This does not exclude the use of the antiserum in non-precipitating antibody-binding techniques if proper controls are included.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Total protein and IgG concentrations in the antiserum are comparable to those of normal pooled swine serum. No foreign proteins added. Antibody titre: Precipitin titre not less than 1:64 when tested against normal human plasma in agar-block immunodiffusio

Buffer: Delipidated, heat inactivated, lyophilized, stable whole serum.

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C, prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by add ing 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not ref rozen, and preferably used the same day.

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: Transthyretin (Prealbumin) (TTR Produkte)

Synonyme: zgc:103583 antikoerper, TTR antikoerper, LOC100226992 antikoerper, CTS antikoerper, CTS1 antikoerper, HsT2651 antikoerper, PALB antikoerper, TBPA antikoerper, AA408768 antikoerper, AI787086 antikoerper, D17860 antikoerper, prealbumin antikoerper, Lr1 antikoerper, Tbpa antikoerper, Prealbumin antikoerper, xTTR antikoerper, transthyretin (prealbumin, amyloidosis type I) antikoerper, transthyretin antikoerper, Transthyretin antikoerper, transthyretin (prealbumin, amyloidosis type 1) antikoerper, transthyretin-like antikoerper, transthyretin L homeolog antikoerper, ttr antikoerper, TTR antikoerper, vpb38 antikoerper, MRAD2831_RS38185 antikoerper, Caci_4246 antikoerper, LOC100226992 antikoerper, Ttr antikoerper, ttr.L antikoerper

Hintergrund: Tested in immunoelectrophoresis and double radial immunodiffusion against normal human serum the precipitin line obtained shows a reaction of full identity with the purified immunogen. The product does not react with any other proteins component of human serum or plasma

Pathways: Hormone Transport