MLV p30 Antikörper

Produktnummer ABIN457547

Produktdetails

Target: MLV p30

Reaktivität: Moloney Murine Leukemia Virus (MoMuLV)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: MLV Gag, p30

Aufreinigung: MLV p30 affinity purified

Immunogen: Full length recombinant MLV-Gag p30 capside protein,purified from E. coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1500. Polyclonal antibody working titer has to be established practically for each particular antigen and assay format

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml

Buffer: Concentrated ammonium sulphide in PBS pH 7.4.

Handhabung: As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use.

Lagerung: 4 °C

Informationen zur Lagerung: This product is shipped in non-frozen liquid form in ambient conditions

Referenzen

Lee, Komano, Saitoh, Yamaoka, Kozaki, Misawa, Takahama, Satoh, Takeuchi, Yamamoto, Matsuura, Saitoh, Akira: "Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 30, pp. 12379-84, (2013) (PubMed).

Antigendetails

Target: MLV p30

Substanzklasse: Viral Protein

Hintergrund: Murine leukemia viruses belong to family ofRetroviruses group and are named for their ability to cause cancer in mice.Some form of MLV’s are used in cancer research. The retroviral Gag protein plays importantroles at several stages in the viral life cycle. Late in infection, the Gagprecursor protein acts to mediate the assembly and release of virion particles.Afterbudding, the core matures by cleavage of Gag precursor protein intothe mature core proteins, the matrix (MA), capsid (CA) andnucleocapsid proteins. These separated Gag proteins then play roles in the early stages ofinfection