ENPP3 Antikörper

Produktnummer ABIN457434

Zitiert in 2+ Publikationen. Der Maus Monoklonal anti-ENPP3 Antikörper (Klon NP4D6) (ABIN457434) detektiert spezifisch ENPP3 in FACS und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ENPP3 Antikörper (ABIN457434)

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ENPP3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: NP4D6

Produktdetails anti-ENPP3 Antikörper

Verwendungszweck: Anti-Hu CD203c Purified

Kreuzreaktivität (Details): Human

Produktmerkmale: The mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: HEK-293 cells transfected with human CD203c

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL. Extracellular and intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-ENPP3 Antikörper (ABIN457434)

Heneberg, Riegerová, Kučera: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).

Platz, Binder, Marxer, Lischka, Valent, Bühring: "Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals." in: International archives of allergy and immunology, Vol. 126, Issue 4, pp. 335-42, (2002) (PubMed).

Details zu ENPP3

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Andere Bezeichnung: CD203c

Hintergrund: Ectonucleotide pyrophosphatase/phosphodiesterase 3,CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.,ENPP3, B10, PDNP3, PD-IBETA

Gen-ID: 5169

UniProt: O14638

Pathways: Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity