ENPP3 Antikörper
(2 Referenzen)Kurzübersicht für ENPP3 Antikörper (ABIN457434)
Target
Alle ENPP3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD203c Purified
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Spezifität
- The mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
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Kreuzreaktivität (Details)
- Human
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Immunogen
- HEK-293 cells transfected with human CD203c
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Isotyp
- IgG1
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anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibody
ENPP3 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 45-163) antibodyENPP3 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 4C1H2 unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibodyENPP3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (APC)ENPP3 Reaktivität: Human FACS Wirt: Maus Monoclonal NP4D6 APC
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (PE)ENPP3 Reaktivität: Human FACS, ICC Wirt: Maus Monoclonal NP4D6 PE
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibodyENPP3 Reaktivität: Human, Hund, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (FITC)ENPP3 Reaktivität: Human FACS Wirt: Maus Monoclonal NP4D6 FITC
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 40-140) antibodyENPP3 Reaktivität: Human, Ratte FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 814-843), (C-Term) antibodyENPP3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB24586 unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 602-699) antibodyENPP3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1G11 unconjugated
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Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Extracellular and intracellular staining.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).
: "Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals." in: International archives of allergy and immunology, Vol. 126, Issue 4, pp. 335-42, (2002) (PubMed).
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: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).
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- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
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Andere Bezeichnung
- CD203c
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Hintergrund
- Ectonucleotide pyrophosphatase/phosphodiesterase 3,CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.,ENPP3, B10, PDNP3, PD-IBETA
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Gen-ID
- 5169
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UniProt
- O14638
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Pathways
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
Target
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