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CD81 Antikörper

Dieses Anti-CD81-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD81 in FACS, WB, IP, IHC (p) und ICC. Geeignet für Human, Kaninchen und Cat. Dieses Primary Antibody wurde in 6+ Publikationen zitiert.
Produktnummer ABIN457431

Kurzübersicht für CD81 Antikörper (ABIN457431)

Target

Alle CD81 Antikörper anzeigen
CD81

Reaktivität

  • 208
  • 143
  • 81
  • 25
  • 25
  • 25
  • 17
  • 16
  • 9
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Kaninchen, Cat

Wirt

  • 118
  • 93
  • 41
  • 11
  • 3
  • 3
  • 1
  • 1
Maus

Klonalität

  • 207
  • 56
  • 4
Monoklonal

Konjugat

  • 111
  • 22
  • 19
  • 18
  • 10
  • 7
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD81 Antikörper ist unkonjugiert

Applikation

  • 197
  • 104
  • 85
  • 51
  • 49
  • 41
  • 35
  • 30
  • 29
  • 25
  • 22
  • 14
  • 14
  • 13
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Klon

M38
  • Verwendungszweck

    Anti-Hu CD81 Purified

    Spezifität

    The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

    Kreuzreaktivität (Details)

    Human, Feline (Cat), Rabbit

    Aufreinigung

    Purified by protein-A affinity chromatography.

    Reinheit

    > 95 % (by SDS-PAGE)

    Immunogen

    MOLT-4 (human T-ALL cell line)

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: recommended dilution: 1 μg/mL.
    Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Do not freeze.
  • Oka, Kobayashi, Matsumura, Nishio, Nakano, Okamura, Okochi, Minamisawa, Shiba, Saeki: "New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6." in: Cells, Vol. 9, Issue 6, (2020) (PubMed).

    Matsumura, Minamisawa, Suga, Kishita, Akagi, Ichiki, Ichikawa, Shiba: "Subtypes of tumour cell-derived small extracellular vesicles having differently externalized phosphatidylserine." in: Journal of extracellular vesicles, Vol. 8, Issue 1, pp. 1579541, (2019) (PubMed).

    Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

    Imai, Kakizaki, Nishimura, Yoshie: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).

    Imai, Yoshie et al.: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).

    Fukudome, Furuse, Imai, Nishimura, Takagi, Hinuma, Yoshie et al.: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen ..." in: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, (1992) (PubMed).

  • Target

    CD81

    Andere Bezeichnung

    CD81

    Hintergrund

    CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

    Gen-ID

    975

    UniProt

    P60033

    Pathways

    Inositol Metabolic Process, Hepatitis C
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