CD81 Antikörper
Kurzübersicht für CD81 Antikörper (ABIN457431)
Target
Alle CD81 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD81 Purified
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Spezifität
- The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
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Kreuzreaktivität (Details)
- Human, Feline (Cat), Rabbit
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Immunogen
- MOLT-4 (human T-ALL cell line)
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Isotyp
- IgG1
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Applikationshinweise
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Flow cytometry: recommended dilution: 1 μg/mL.
Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6." in: Cells, Vol. 9, Issue 6, (2020) (PubMed).
: "Subtypes of tumour cell-derived small extracellular vesicles having differently externalized phosphatidylserine." in: Journal of extracellular vesicles, Vol. 8, Issue 1, pp. 1579541, (2019) (PubMed).
: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).
: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).
: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).
: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen ..." in: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, (1992) (PubMed).
: "
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New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6." in: Cells, Vol. 9, Issue 6, (2020) (PubMed).
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- CD81
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Andere Bezeichnung
- CD81
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Hintergrund
- CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28
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Gen-ID
- 975
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UniProt
- P60033
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Pathways
- Inositol Metabolic Process, Hepatitis C
Target
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