YDJ1 Antikörper

Produktnummer ABIN453928

Dieser Maus Monoklonal Antikörper detektiert spezifisch YDJ1 in IP, WB und EIA. Es zeigt Reaktivität gegenüber Proben von Saccharomyces cerevisiae.

Kurzübersicht für YDJ1 Antikörper (ABIN453928)

Target: YDJ1 (HSP40 / YDJ1 (YDJ1))

Reaktivität: Saccharomyces cerevisiae

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YDJ1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 2A7-H6

Produktdetails anti-YDJ1 Antikörper

Spezifität: This antibody detects Hsp40 / Ydj1 at ~40 kDa.

Keine Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Species reactivity (tested):Yeast.

Aufreinigung: Protein G chromatography

Immunogen: Full length protein HSP40 (YDJ1)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot: 1 - 2000. ELISA. Immunoprecipitaion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: 0.09 % sodium azide in 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu YDJ1

Target: YDJ1 (HSP40 / YDJ1 (YDJ1))

Andere Bezeichnung: YDJ1 / MAS5

Hintergrund: Human Hsp40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein) (1). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain (2). There are two main types of Hsp40, type 1 DNAJ proteins including HDJ2 and yeast YdjI, type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding. (3, 4), type II does not. Members of the Hsp40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. Hsp40 stimulates the ATPase activity of Hsp70 which in turn causes conformational changes of the unfolded proteins (5, 6). The Hsp40-Hsp70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1 (7).Synonyms: Mitochondrial protein import protein MAS5, Yeast dnaJ protein 1

Gen-ID: 850779

UniProt: P39102